Rhabdomyolysis: Causes and Symptoms

The life threatening syndrome due to a direct or indirect muscle injury is known as rhabdomyolysis. Rhabdomyolysis results from the death of muscle fibers and release of their contents into the bloodstream. This can lead to serious complications such as renal failure. The kidneys cannot remove waste and concentrated urine in case of renal failure. Rhabdomyolysis can even leads to death in rare cases. However, for a good outcome prompt treatment is required.


Symptoms:

The initial symptoms of rhabdomyolysis include: fatigue, low urine output, muscle weakness, nausea, vomiting, confusion, agitation, infrequent urination and fever.

The complications of rhabdomyolysis include very high levels of potassium in the blood.  That can leads to an irregular heartbeat or cardiac arrest, kidney damage (which occurs in up to half of patients), rarely liver damage. After fluid resuscitation a condition called compartment syndrome may also occur. Due to serious compression of nerves, muscles, and blood vessels can cause tissue damage and problems with blood flow.


Causes of rhabdomyolysis:

Trauma, exertion, and heat: The causes include a crush injury, a heatstroke, blocked blood vessels, a lightning strike, pathological muscle exertion and car accident.

Metabolic and genetic disorders: Rhabdomyolysis can be developed in some people because of genetic conditions such as problems with metabolism of: lipids, or fats, carbohydrates.

Metabolic problems includes: hypothyroidism or low thyroid hormone levels, diabetic ketoacidosis
Genetic disorders include: a carnitine deficiency, a lactate dehydrogenase deficiency, infection and inflammation, duchenne muscular dystrophy.

The infection and inflammation can cause rhabdomyolysis, including: viral infections, bacterial infections, polymyositis, dermatomyositis and snakebites.



Comments

Post a Comment

Popular posts from this blog

Newborn screening for critical congenital heart disease using pulse oximetry

Image
Newborn screening for critical congenital heart disease using pulse oximetry: The most common congenital disorder in newborns is congenital heart disease (CHD). In the first year of life requiring surgery or catheter- based intervention is known as Critical CHD. Normally in case of infants with critical cardiac lesions, the risk of morbidity and mortality increases when there is a delay in diagnosis and timely referral to a tertiary center with expertise in treating these patients. Pulse oximetry:   it is a non-invasive method for monitoring a person's oxygen saturation. The application mode of pulse oximetry includes, a sensor device is placed on a thin part of the patient's body, usually a fingertip or earlobe, or in the case of an infant, across a foot. In this process the device passes two wavelengths of light through the body part to a photodetector.  The changing absorbance at each of the wavelength are measured by this, which allowing it to determine the
Read more

Acute Abdomen Symptoms and Management:

Image
Acute Abdomen Symptoms and Management: The acute abdomen shows a rapid onset of severe life- threatening symptoms includes the sudden, spontaneous, nontraumatic disorder whose chief manifestation is in the abdominal area.  For acute abdomen urgent operation may be necessary. Acute abdomen has a large number of possible causes and so a structured approach is required. If the patient has an acute surgical problem the initial assessment for acute abdomen should attempt that requires immediate and prompt surgical intervention, or urgent medical therapy. Abdominal pain is a common problem. Symptoms and Causes: Vomiting, Haematemesis or melaena, Stool/urine colour, Fainting, dizziness or palpitations, Fever/rigors, Rash or itching, Urinary symptoms, recent weight loss. Some common causes of acute abdomen usually involve a slower rate of bleeding, but with urgent surgery still required, include bleeding gastric ulcer, ruptured ectopic pregnancy, and trauma.  Every pa
Read more

Bronchitis (Acute) Symptoms, Causes, Treatment, and Cures:

Image
Bronchitis (Acute) Symptoms, Causes, Treatment, and Cures: An inflammation of the lining of your bronchial tubes is known as Bronchitis. There are two types of bronchitis    1) acute bronchitis, and 2) chronic bronchitis. Acute bronchitis is defined as a cough lasting five or more days also known as a chest cold, the cough may linger for weeks. In some cases people with recurrent acute bronchitis develop chronic bronchitis and a respiratory infection. Chronic bronchitis is known to be lasts for at least 3 months, 2 years in a row. It is defined as a cough that occurs every day with sputum production.   Medical attention is required for chronic bronchitis. Chronic bronchitis is one of the conditions included in chronic obstructive pulmonary disease (COPD). Viral or bacterial infection are the most common way for infection, due to this people become infected with or “get” acute bronchitis.   Irritants like tobacco smoke, air pollution, or chemicals are the other causes.
Read more